{"id":"oxtr-qrc-01","section":"continuation","availableSections":["summary","sequences","methods","measurements","comparison","next_test","timing","downloads","continuation"],"data":{"question":"Do regular Fibonacci sequences, M9 P24 including Alpha, Beta, Gamma and Epsilon, and Phi Ratio help predict transcription factor binding around OXTR?","interpretation":{"answer":"There is no demonstrated benefit yet for predicting binding around OXTR. Adding Fibonacci and Phi Ratio features gave an inconclusive result. The new classical test did not evaluate biological prediction by M9 P24 Alpha, Beta, Gamma or Epsilon. This pilot concerns CTCF, one DNA-binding protein measured in one stem-cell context, not transcription factors generally.","what_we_did":"The agent completed a comparison of ordinary DNA binding-pattern and spacing features, with and without Fibonacci/Phi Ratio features. It learned on chromosome 1, chose the method on chromosome 2 and tested OXTR on chromosome 3, without seeing OXTR laboratory answers during learning or selection. The agent also prepared a new matched pair of DNA windows: one overlapping a reported CTCF peak and one comparison window. For each, it compiled the same DNA eight ways—ordinary, Fibonacci, Phi Ratio, Alpha, Beta, Gamma, Epsilon and shuffled controls—and completed 16 local CUDA-Q CPU checks.","meaning":"At OXTR, average precision rose from 0.0719 to 0.0739. This is a ranking score, not percent accuracy. The uncertainty range for the change extended from −0.0263 to +0.0082, leaving benefit unresolved; the noisy increase establishes no advantage. The pilot covered only five OXTR peak regions and used laboratory data with quality warnings. Saved CUDA-Q/Aquila readings describe programmed atom excitation, not binding probabilities; the two saved samples overlap none of those peaks, so they do not validate binding prediction. The new matched pair checks programs, not predictive performance.","next_dependency":"A larger quantum prediction test still needs more matched quantum measurements linked to laboratory binding results, and a larger independent biological test remains necessary. Today’s instruction prohibits new Aquila submissions; none were made, and no new quantum jobs were submitted. Fresh device validation and explicit allowance are required before Aquila submission; new paid qBraid work also lacks a credit allowance. This is an automated preliminary report, with Gemini oversight deferred. The inconclusive result usefully separates completed program checks from evidence of predictive benefit."},"review":{"status":"automated_preliminary","Gemini":"deferred_by_owner"},"metrics":{"difference_average_precision":0.0019879267780844173,"block_bootstrap_95_interval":[-0.026260195602900528,0.008181524055569506],"counts":{"development":{"windows":64,"peak_windows":32},"validation":{"windows":64,"peak_windows":32},"OXTR test":{"windows":152,"peak_windows":8}}},"local_cudaq_cases":16,"spend":{"new_Aquila_USD":0,"new_qBraid_credits":0}},"sourceSHA256":"adc1914cac349c28afc5f4d8c72dbddf80f38063ab1bef3e93e21cea8d415876","url":"https://universalmind.tv/informatics/quantum/experiments/oxtr-agent-follow-through-pilot/r1/experiment.json","pageURL":"https://universalmind.tv/informatics/?area=quantum&entry=research"}